Chitosan functionalised nanopipettes

chitosan

The polysaccharide chitosan is the structural element in the exoskeleton of crustaceans (crabs, shrimp, etc.) and is known to form complexes with metal ions. In this paper, we show that a nanopipette functionalised with chitosan can reversibly bind metal ions, resulting in a reversible, real-time signal that is concentration dependent.

 

 

Nanoprecipitation in a nanopipette

precipation

Studying the earliest stages of precipitation at the nanoscale is technically challenging but quite valuable as such phenomena reflect important processes such as crystallization and biomineralization. Using a nanopipette as a nanoreactor, we induced precipitation of an insoluble salt to generate oscillating current blockades.

Mycotoxin detection by nanopipette

fungus

Mycotoxins are secondary metabolites produced by fungi that are capable of causing disease and death in humans and animals. In this paper, we showed that antibody functionalized nanopipettes can detect HT-2 toxin with a detection limit of 100 fg/ml and compared the results with conventional sandwich assay techniques.